Best 420 Friendly Hotels on Las Vegas Strip

We checked thousands of reviews on and to find the best hotels for your stay
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Judy Hebron

Updated: 03 September 2024 · 2 min

Las Vegas, often referred to as the Entertainment Capital of the World, beckons visitors with its dazzling lights, vibrant nightlife, and world-class entertainment. Nestled along the iconic Las Vegas Strip are a plethora of luxurious hotels that cater to every traveler's needs and desires. For those seeking a more laid-back and unique experience, the emergence of 420 friendly hotels on Las Vegas Strip has opened up a whole new dimension of hospitality options.

Imagine checking into a stylish hotel on the Las Vegas Strip, where you are not only welcomed with impeccable service but also with a cannabis-friendly atmosphere. These 420 friendly hotels offer a safe and welcoming environment for guests who appreciate the combination of relaxation and indulgence. Whether you are a seasoned cannabis enthusiast or just curious to explore, these accommodations provide a discreet and comfortable setting to enjoy your stay in Las Vegas.

Indulge in the ultimate vacation experience as you unwind in a 420 friendly hotel on the Las Vegas Strip, where the city's renowned attractions are just steps away. From upscale dispensaries to rooftop lounges with stunning views, these accommodations ensure that every aspect of your Las Vegas getaway is memorable. Embrace the fusion of luxury and cannabis culture as you immerse yourself in the vibrant energy of Las Vegas, making your stay truly exceptional.
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Our Top 3

(Sorted by rating & number of reviews)

1. Palomino Motel
2. Historic Plaza Hotel
3. Days Inn By Wyndham Las Vegas

420 Friendly Hotels on Las Vegas Strip

Check Availability

Las Vegas
Mar 08, 2026 - Mar 09, 2026

Palomino Motel

7.9

Good

(359 Reviews)

+ 11 photos
The Palomino Motel is a hidden gem along the Las Vegas Strip, known for its laid-back atmosphere and cannabis-friendly policies. Guests can relax in cozy rooms and enjoy convenient access to nearby dispensaries and cannabis-themed activities. With a focus on hospitality and inclusivity, this motel offers a welcoming retreat for travelers looking to experience Las Vegas through a cannabis-friendly lens.
Address: 1330 Grand Ave
Rating: Good 7.9 (359 Reviews)
Price: From 55$

420 Friendly Hotels on Las Vegas Strip

Historic Plaza Hotel

8.5

Good

(1270 Reviews)

+ 57 photos
Nestled in the center of downtown Las Vegas, the Historic Plaza Hotel exudes old-world charm while embracing modern cannabis culture. With designated smoking areas and a relaxed atmosphere, guests can enjoy their favorite cannabis products in a discreet setting. The hotel's elegant decor and personalized service create a truly immersive experience for visitors seeking a unique stay on the Las Vegas Strip.
Address: 230 Plaza Street
Rating: Good 8.5 (1270 Reviews)
Rooms: 70
Price: From 109$

Days Inn By Wyndham Las Vegas

6.8

Good

(348 Reviews)

+ 32 photos
Conveniently located near popular attractions, the Days Inn By Wyndham Las Vegas offers a relaxed and welcoming environment for cannabis-friendly travelers. Guests can unwind in comfortable rooms and take advantage of the hotel's proximity to dispensaries and cannabis-friendly lounges. Whether you're a seasoned cannabis connoisseur or a curious beginner, this hotel provides a convenient base for exploring the vibrant cannabis scene in Las Vegas.
Address: 2000 Grand Avenue
Rating: Good 6.8 (348 Reviews)
Rooms: 36
Price: From 72$